| Compound ID |
Compound Name |
Compound Formula |
|
CP0145618
|
N-[N'-[[4-[[2-(azetidin-1-yl)acetyl]amino]-3-chloro-5-methylphenyl]methyl]carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
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|
C26H29ClN6O3S
|
2
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
|
CP0427661
|
N-[N'-[[4-[[2-(azetidin-1-yl)acetyl]amino]-3,5-dichlorophenyl]methyl]carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
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|
C25H26Cl2N6O3S
|
2
|
| 1 |
IC50 = 8 nM
|
|
|
| 2 |
IC50 = 180 nM
|
|
|
|
CP0481039
|
N-[N'-[(4-acetamido-3,5-dichlorophenyl)methyl]carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
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|
C22H21Cl2N5O3S
|
2
|
| 1 |
IC50 = 310 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0379875
|
N-[N'-[(4-amino-3,5-dichlorophenyl)methyl]carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide
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|
C20H19Cl2N5O2S
|
2
|
| 1 |
IC50 = 1030 nM
|
|
|
| 2 |
IC50 = 1700 nM
|
|
|
|
CP0379882
|
N-[N'-[(3,5-dichlorophenyl)methyl]carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxamide
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|
C20H18Cl2N4O3
|
2
|
| 1 |
IC50 = 3300 nM
|
|
|
| 2 |
IC50 = 3900 nM
|
|
|
