Brief Information of the Compound and Protein
Compound Name
N-[(3R)-3-[4-[4-methoxy-N-(thiophen-3-ylmethyl)anilino]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
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PubChem ID
CID: 71458736
Canonical SMILES
COc1ccc(cc1)N(Cc1ccsc1)C1CCN(CC1)[C@H](C)CCNC(=O)c1c(C)ncnc1C
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Compound Formula C28H37N5O2S
Compound Structure
Protein Name
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000517 P4 MAGI CCR5+ Homo sapiens (Human)  1
1
IC50 = 1.2 nM
   TI
   LI
   LO
   TS