Brief Information of the Compound and Protein
Compound Name
1-methyl-5-(2-oxo-1,3-dihydroindol-5-yl)pyrrole-2-carbonitrile
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PubChem ID
CID: 11608377
SID: 16711164
Canonical SMILES
Cn1c(ccc1-c1ccc2NC(=O)Cc2c1)C#N
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Compound Formula C14H11N3O
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 80 nM
   TI
   LI
   LO
   TS