Brief Information of the Compound and Protein
Compound Name
2,2-Dimethyl-propionic acid 6-(5-cyano-thiophen-3-yl)-4,4-dimethyl-2-trifluoromethyl-4H-benzo[d][1,3]oxazin-1-ylmethyl ester
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PubChem ID
CID: 23435583
Canonical SMILES
CC(C)(C)C(=O)OCN1C(OC(C)(C)c2cc(ccc12)-c1csc(c1)C#N)C(F)(F)F
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Compound Formula C22H23F3N2O3S
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  2
1
EC50 = 0.9 nM
   TI
   LI
   LO
   TS
2
IC50 = 7.9 nM
   TI
   LI
   LO
   TS