Brief Information of the Compound and Protein
Compound Name
5-(3,3-diethyl-2-oxo-1H-indol-5-yl)-1-methylpyrrole-2-carbonitrile
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PubChem ID
CID: 24824069
SID: 49840273
Canonical SMILES
CCC1(CC)C(=O)Nc2ccc(cc12)-c1ccc(C#N)n1C
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Compound Formula C18H19N3O
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  2
1
IC50 = 3.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 36 nM
   TI
   LI
   LO
   TS