Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-chloro-4-(isobutyl(3-methyl-1-(1-methyl-1H-tetrazol-5-yl)butyl)amino)benzonitrile
    Show/Hide
 PubChem ID
CID: 45269807
Canonical SMILES
CC(C)CC(N(CC(C)C)c1ccc(C#N)c(Cl)c1)c1nnnn1C
    Show/Hide
Compound Formula C18H25ClN6
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 9.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM