Brief Information of the Compound and Protein
Compound Name
2,2,4-Trimethyl-6-thiophen-2-yl-1,2-dihydro-quinoline
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PubChem ID
CID: 44355053
Canonical SMILES
CC1=CC(C)(C)Nc2ccc(cc12)-c1cccs1
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Compound Formula C16H17NS
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 416 nM
   TI
   LI
   LO
   TS
CL000078 T-47D Homo sapiens (Human)  1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 234.42 nM
2 Ki = 237 nM