Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-chloro-4-((5-fluoro-2-methylbenzyl)((S)-1-((S)-2-hydroxypropanoyl)pyrrolidin-3-yl)amino)benzonitrile
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 PubChem ID
CID: 24990837
SID: 56332800
Canonical SMILES
C[C@H](O)C(=O)N1CC[C@@H](C1)N(Cc1cc(F)ccc1C)c1ccc(C#N)c(Cl)c1
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Compound Formula C22H23ClFN3O2
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 183 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 79 nM