General Information of the Compound
Compound ID
CP0458658
Compound Name
4,4-bis(4-chlorophenyl)-6-(3-chlorophenylamino)-1-methyl-1H-benzo[d][1,3]oxazin-2(4H)-one
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Structure
Formula
C27H19Cl3N2O2
Molecular Weight
509.82
Canonical SMILES
CN1C(=O)OC(c2ccc(Cl)cc2)(c2ccc(Cl)cc2)c2cc(Nc3cccc(Cl)c3)ccc12
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InChI
InChI=1S/C27H19Cl3N2O2/c1-32-25-14-13-23(31-22-4-2-3-21(30)15-22)16-24(25)27(34-26(32)33,17-5-9-19(28)10-6-17)18-7-11-20(29)12-8-18/h2-16,31H,1H3
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InChIKey
DPABUIRNVQEIGL-UHFFFAOYSA-N
Physicochemical Property
logP
8.2687
Rotatable Bonds
4
Heavy Atom Count
34
Polar Areas
41.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44438268
ChEMBL ID
CHEMBL392704
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01172, Progesterone receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  1
1
IC50 = 1000 nM
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