Brief Information of the Compound and Protein
Compound Name
1-methyl-5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile
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PubChem ID
CID: 11210694
SID: 16293161
Canonical SMILES
Cn1c(ccc1-c1ccc2NC(=O)COC(C)(c3cccs3)c2c1)C#N
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Compound Formula C20H17N3O2S
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  2
1
EC50 = 0.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.4 nM
   TI
   LI
   LO
   TS