General Information of the Compound
Compound ID
CP0509942
Compound Name
4,4-dibenzyl-6-(3-chlorophenyl)-1H-3,1-benzoxazine-2-thione
    Show/Hide
Structure
Formula
C28H22ClNOS
Molecular Weight
456.01
Canonical SMILES
Clc1cccc(c1)-c1ccc2NC(=S)OC(Cc3ccccc3)(Cc3ccccc3)c2c1
    Show/Hide
InChI
InChI=1S/C28H22ClNOS/c29-24-13-7-12-22(16-24)23-14-15-26-25(17-23)28(31-27(32)30-26,18-20-8-3-1-4-9-20)19-21-10-5-2-6-11-21/h1-17H,18-19H2,(H,30,32)
    Show/Hide
InChIKey
FNXHYOFYGFDMGS-UHFFFAOYSA-N
Physicochemical Property
logP
7.4147
Rotatable Bonds
5
Heavy Atom Count
32
Polar Areas
21.26
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44275352
ChEMBL ID
CHEMBL277644
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01172, Progesterone receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  1
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS