Brief Information of the Compound and Protein
Compound Name
5-(7-fluoro-2-oxospiro[1H-indole-3,1'-cyclopentane]-5-yl)-1-methylpyrrole-2-carbonitrile
    Show/Hide
PubChem ID
CID: 24824071
SID: 49840276
Canonical SMILES
Cn1c(ccc1-c1cc2c(NC(=O)C22CCCC2)c(F)c1)C#N
    Show/Hide
Compound Formula C18H16FN3O
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  3
1
EC50 = 3000 nM
   TI
   LI
   LO
   TS
2
IC50 = 3.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 14.7 nM
   TI
   LI
   LO
   TS