General Information of the Compound
Compound ID
CP0554701
Compound Name
2-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4-propyl-5H-phenanthridin-6-one
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Structure
Formula
C19H15F6NO2
Molecular Weight
403.322
Canonical SMILES
CCCc1cc(cc2c3ccccc3c(=O)[nH]c12)C(O)(C(F)(F)F)C(F)(F)F
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InChI
InChI=1S/C19H15F6NO2/c1-2-5-10-8-11(17(28,18(20,21)22)19(23,24)25)9-14-12-6-3-4-7-13(12)16(27)26-15(10)14/h3-4,6-9,28H,2,5H2,1H3,(H,26,27)
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InChIKey
UUPGJEIOTSHDTL-UHFFFAOYSA-N
Physicochemical Property
logP
4.946
Rotatable Bonds
3
Heavy Atom Count
28
Polar Areas
53.09
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145960034
ChEMBL ID
CHEMBL4163940
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01172, Progesterone receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  1
1
IC50 = 360 nM
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