General Information of the Compound
| Compound ID |
CP0449766
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| Compound Name |
(8S,11R,13S,14R,17S)-17-(3,5-difluoro-phenylethynyl)-11-(4-dimethylamino-phenyl)-17-hydroxy-13-methyl-1,2,8,11,12,13,14,15,16,17-decahydro-6H-7-oxa-cyclopenta[a]phenanthren-3-one
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| Structure |
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| Formula |
C33H33F2NO3
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| Molecular Weight |
529.627
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| Canonical SMILES |
CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cc(F)cc(F)c2)[C@@H]2OCC3=CC(=O)CCC3=C12
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| InChI |
InChI=1S/C33H33F2NO3/c1-32-18-28(21-4-6-25(7-5-21)36(2)3)30-27-9-8-26(37)16-22(27)19-39-31(30)29(32)11-13-33(32,38)12-10-20-14-23(34)17-24(35)15-20/h4-7,14-17,28-29,31,38H,8-9,11,13,18-19H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1
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| InChIKey |
PUBSQRWHEBSORN-ZDRBTZMISA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00967, Glucocorticoid receptor
Protein ID: PT01172, Progesterone receptor