Brief Information of the Compound and Protein
Compound Name
3-(4,4-Dimethyl-2-thiophen-2-yl-1,4-dihydro-2H-benzo[d][1,3]oxazin-6-yl)-5-fluoro-benzonitrile
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PubChem ID
CID: 44378690
Canonical SMILES
CC1(C)OC(Nc2ccc(cc12)-c1cc(F)cc(c1)C#N)c1cccs1
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Compound Formula C21H17FN2OS
Compound Structure
Protein Name
Progesterone receptor
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D Homo sapiens (Human)  3
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
IC50 = 51.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 1682 nM
   TI
   LI
   LO
   TS