General Information of the Cell Line
Cell Line ID
CL000209
Cell Line Name
HEC-1
Synonyms
HEC1
Human Endometrial Cancer-1
HEC-B-296
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1274
Tissue Information
Endometrium
Disease
Endometrial adenocarcinoma (NCIt: C7359)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00886, Estrogen receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0006292
 Compound Info 
(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol
   Show/Hide
C18H24O2
  1
1
EC50 = 0.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0089686
 Compound Info 
6-[(3S,4R)-4-(4-hydroxyphenyl)hexan-3-yl]pyridin-3-ol
   Show/Hide
C17H21NO2
  1
1
EC50 = 0.11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0192375
 Compound Info 
6-[(2R,3S)-2-(4-hydroxyphenyl)pentan-3-yl]pyridin-3-ol
   Show/Hide
C16H19NO2
  1
1
EC50 = 0.11 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0228060
 Compound Info 
1,2-Bis-(4-hydroxy-phenyl)-but-1-ene
   Show/Hide
C16H16O2
  1
1
EC50 = 0.52 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0062376
 Compound Info 
(+/-)-1,2-Bis-(4-hydroxy-phenyl)-pentane
   Show/Hide
C17H20O2
  1
1
EC50 = 2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0167248
 Compound Info 
(+/-)-1,2-Bis-(4-hydroxy-phenyl)-propane
   Show/Hide
C15H16O2
  1
1
EC50 = 6.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0302514
 Compound Info 
(+/-)-1,2-Bis-(4-hydroxy-phenyl)-2-methyl-butane
   Show/Hide
C17H20O2
  1
1
EC50 = 10.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0037944
 Compound Info 
1,2-Bis-(4-hydroxy-phenyl)-prop-1-ene
   Show/Hide
C15H14O2
  1
1
EC50 = 11.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0194124
 Compound Info 
6-[(3S,4S)-4-(4-hydroxyphenyl)hexan-3-yl]pyridin-3-ol
   Show/Hide
C17H21NO2
  1
1
EC50 = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0037942
 Compound Info 
1,2-Bis-(4-hydroxy-phenyl)-2-methyl-propane
   Show/Hide
C16H18O2
  1
1
EC50 = 16.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0129262
 Compound Info 
(+/-)-1,2-Bis-(4-hydroxy-phenyl)-2-methyl-pentane
   Show/Hide
C18H22O2
  1
1
EC50 = 20.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0148379
 Compound Info 
6-[1-(4-Hydroxy-benzyl)-propyl]-pyridin-3-ol
   Show/Hide
C15H17NO2
  1
1
EC50 = 65 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0062960
 Compound Info 
(+/-)-2,3-bis(4-hydroxyphenyl)propanenitrile
   Show/Hide
C15H13NO2
  1
1
EC50 = 66 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0129115
 Compound Info 
1,2-Bis-(4-hydroxy-phenyl)-ethane
   Show/Hide
C14H14O2
  1
1
EC50 = 75.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0192376
 Compound Info 
6-[2-(4-Hydroxy-phenyl)-1-methyl-ethyl]-pyridin-3-ol
   Show/Hide
C14H15NO2
  1
1
EC50 = 330 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0089688
 Compound Info 
6-[2-(4-Hydroxy-phenyl)-propyl]-pyridin-3-ol
   Show/Hide
C14H15NO2
  1
1
EC50 = 440 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0070777
 Compound Info 
2-N-benzyl-6-(3-methylbutyl)-4-N-(2-methylpropyl)pyrimidine-2,4-diamine
   Show/Hide
C20H30N4
  1
1
IC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0218569
 Compound Info 
4-N-benzyl-2-N-(2-methylpropyl)-6-(2-phenylethyl)pyrimidine-2,4-diamine
   Show/Hide
C23H28N4
  1
1
IC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0166666
 Compound Info 
2-N,4-N-bis(2-methylpropyl)-6-(2-phenylethyl)pyrimidine-2,4-diamine
   Show/Hide
C20H30N4
  1
1
IC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0233919
 Compound Info 
2,4-diisobutylamino-6-(1-naphthylethyl)-pyrimidine
   Show/Hide
C24H32N4
  1
1
IC50 = 2100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0170009
 Compound Info 
2-N,4-N,6-N-tris(2-methylpropyl)pyrimidine-2,4,6-triamine
   Show/Hide
C16H31N5
  1
1
IC50 = 2400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0151573
 Compound Info 
2,4-diisobutylamino-6-isopentylpyrimidine
   Show/Hide
C17H32N4
  1
1
IC50 = 3100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138830
 Compound Info 
6-(3-methylbutyl)-4-N-(2-methylpropyl)-2-N-(naphthalen-1-ylmethyl)pyrimidine-2,4-diamine
   Show/Hide
C24H32N4
  1
1
IC50 = 4100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0092026
 Compound Info 
4-N-methyl-2-N,4-N-bis(2-methylpropyl)-6-(2-naphthalen-1-ylethyl)pyrimidine-2,4-diamine
   Show/Hide
C25H34N4
  1
1
IC50 = 4400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0127394
 Compound Info 
2-N-benzyl-4-N-(2-methylpropyl)-6-(2-phenylethyl)pyrimidine-2,4-diamine
   Show/Hide
C23H28N4
  1
1
IC50 = 4500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0310568
 Compound Info 
4-N-methyl-2-N,4-N-bis(2-methylpropyl)-6-(2-phenylethyl)pyrimidine-2,4-diamine
   Show/Hide
C21H32N4
  1
1
IC50 = 5500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0218572
 Compound Info 
4-N-benzyl-6-(3-methylbutyl)-2-N-(2-methylpropyl)pyrimidine-2,4-diamine
   Show/Hide
C20H30N4
  1
1
IC50 = 5800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0288246
 Compound Info 
6-(3-methylbutyl)-2-N-(2-methylpropyl)-4-N-(naphthalen-1-ylmethyl)pyrimidine-2,4-diamine
   Show/Hide
C24H32N4
  1
1
IC50 = 6700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0211679
 Compound Info 
2-N,4-N-bis(2-methylpropyl)-6-[(E)-2-phenylethenyl]pyrimidine-2,4-diamine
   Show/Hide
C20H28N4
  1
1
IC50 = 6900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0262823
 Compound Info 
6-(3-methylbutyl)-2-(2-methylpropoxy)-N-(2-methylpropyl)pyrimidin-4-amine
   Show/Hide
C17H31N3O
  1
1
IC50 = 6900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0138831
 Compound Info 
6-ethyl-2,4-diisobutylaminopyrimidine
   Show/Hide
C14H26N4
  1
1
IC50 = 7300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0259343
 Compound Info 
2,4-Dibenzylamino-6-isopentylpyrimidine
   Show/Hide
C23H28N4
  1
1
IC50 = 8300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0091992
 Compound Info 
4-benzyl-2,6-diisobutylamino-pyrimidine
   Show/Hide
C19H29N5
  1
1
IC50 = 9500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0091990
 Compound Info 
2-N-methyl-6-(3-methylbutyl)-2-N,4-N-bis(2-methylpropyl)pyrimidine-2,4-diamine
   Show/Hide
C18H34N4
  1
1
IC50 = 9700 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0068040
 Compound Info 
4-N-benzyl-2-N-(2-methylpropyl)-6-[(E)-2-phenylethenyl]pyrimidine-2,4-diamine
   Show/Hide
C23H26N4
  1
1
IC50 = 9800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0206756
 Compound Info 
2-N-benzyl-4-N-(2-methylpropyl)-6-[(E)-2-phenylethenyl]pyrimidine-2,4-diamine
   Show/Hide
C23H26N4
  1
1
IC50 = 12000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0070778
 Compound Info 
6-Butyl-N*2*,N*4*-dipropyl-pyrimidine-2,4-diamine
   Show/Hide
C14H26N4
  1
1
IC50 = 13000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT07153, Envelope glycoprotein gp160
 Protein Info 
Protein ID: PT06335, Envelope glycoprotein gp70
 Protein Info 
Protein ID: PT00889, Estrogen receptor beta
 Protein Info 
Protein ID: PT06742, Gag polyprotein
 Protein Info 
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Endometrium)
Cell Line Name Organism Disease
Ishikawa
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma
HEC-1-B
 Cell Line Info 
Homo sapiens (Human) Endometrial adenocarcinoma