General Information of the Protein
Protein ID |
PT06742
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Protein Name |
Gag polyprotein
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Gene Name |
GAG
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Sequence |
REEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEMGETTVQRDAKMAPEKMATPKTVGTSCYQCGTATGCNCVTASAPPPPYVGSGLYPSLAGAGEQGQGGDTPRGAEQPRAEPGHAGQAPGPALTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPEDTRWLDGKHKRKSSQCLVKSSMSGYIPSCLDKDEQCVVCGDKATGYHYRCITCEGCKSFFRRTIQKNLHPTYSCTYDGCCVIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRKLIEENRERRRKEEMIKSLQHRPSPSAEEWELIHVVTEAHRSTNAQGSHWKQRRKFLLEDIGQSPMASMLDGDKVDLEAFSEFTKIITPAITRVVDFAKNLPMFSELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLSAFNLDDTEVALLQAVLLMSSDRTGLICVDKIEKCQESYLLAFEHYINYRKHNIPHFWSKLLMKVADLRMIGAYHASRFLHMKVECPTELSPQEV
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Organism |
Avian erythroblastosis virus (strain ES4)
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Protein Classification |
Surface antigen
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Function |
Acts as a thyroid-hormone receptor antagonist. The v-ErbA oncogene cooperates with v-ErbB and other primarily sarcoma-inducing oncogenes in transformation of erythroblasts. It is non transforming by itself and cannot induce self-renewal of erythroblasts. Instead it blocks the residual capacity of the v-ErbB cells to differentiate terminally.
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Uniprot ID |
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Subcellular Location |
Virion
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Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000209 , HEC-1
Similar Protein(s) and Bioactivity Statistics
50% Identity
Protein ID | Protein Name | Protein Organism | |
PT01591 | Thyroid hormone receptor alpha | Homo sapiens, Human |
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