Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT03543 , Lysine-specific demethylase 5C
Gene Name KDM5C
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID P41229
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043  Protein ID: PT03543
 
Compound ID Compound Name Compound Formula
CP0088651
3-[(3-methylthiophen-2-yl)methylamino]pyridine-4-carboxylic acid
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C12H12N2O2S
 1
1
IC50 = 25118.86 nM
   TI
   LI
   LO
   TS
CP0796600
2-(4-Chloro-3-hydroxyphenoxy)pyrido[3,4-d]pyrimidin-4(3H)-one
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C13H8ClN3O3
 1
1
IC50 = 31622.78 nM
   TI
   LI
   LO
   TS
CP0695082
2-((6-Isopropylpyridin-3-yl)oxy)pyrido[3,4-d]pyrimidin-4(3H)-one
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C15H14N4O2
 1
1
IC50 = 50118.72 nM
   TI
   LI
   LO
   TS
CP0088649
3-(furan-2-ylmethylamino)pyridine-4-carboxylic acid
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C11H10N2O3
 1
1
IC50 = 63095.73 nM
   TI
   LI
   LO
   TS
CP0181307
2-(1-benzylpyrazol-4-yl)oxy-3H-pyrido[2,3-d]pyrimidin-4-one
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C17H13N5O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0067096
2-[(3-methylthiophen-2-yl)methylamino]pyridine-3-carboxylic acid
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C12H12N2O2S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0067103
2-(furan-2-ylmethylamino)pyridine-3-carboxylic acid
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C11H10N2O3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS