Brief Information of the Compound and Protein
Compound Name
2-((6-Isopropylpyridin-3-yl)oxy)pyrido[3,4-d]pyrimidin-4(3H)-one
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PubChem ID
CID: 136053683
Canonical SMILES
CC(C)c1ccc(Oc2nc3cnccc3c(=O)[nH]2)cn1
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Compound Formula C15H14N4O2
Compound Structure
Protein Name
Lysine-specific demethylase 5C
Protein Classification
Epigenetic regulator
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Plant homeodomain
Uniprot ID
P41229
Gene Name
KDM5C
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 125.89 nM
   TI
   LI
   LO
   TS
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 50118.72 nM
   TI
   LI
   LO
   TS