Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT01631 , Mineralocorticoid receptor
 Protein Info 
Gene Name NR3C2
Organism Rattus norvegicus, Rat
Protein Classification Transcription factor
Uniprot ID P22199
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT01631
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0233173
 Compound Info 
[(3R)-7-fluoro-4-(3-oxo-4H-1,4-benzoxazine-6-carbonyl)-2,3-dihydro-1,4-benzoxazin-3-yl]methanesulfonamide
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C18H16FN3O6S
  1
1
IC50 = 7.943 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0233170
 Compound Info 
US10017502, Example 6b
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C20H18ClN3O5
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0100868
 Compound Info 
methyl (1R,2S,9R,10R,11S,14R,15S,17R)-2,15-dimethyl-5,5'-dioxospiro[18-oxapentacyclo[8.8.0.01,17.02,7.011,15]octadec-6-ene-14,2'-oxolane]-9-carboxylate
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C24H30O6
  1
1
IC50 = 39.81 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0244392
 Compound Info 
2-[(3S)-6-chloro-4-(3-oxo-4H-1,4-benzoxazine-6-carbonyl)-2,3-dihydro-1,4-benzoxazin-3-yl]-N-methylacetamide
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C20H18ClN3O5
  1
1
IC50 = 79.43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0536855
 Compound Info 
US10017502, Example 4b
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C20H18FN3O5
  1
1
IC50 = 79.43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0368938
 Compound Info 
6-[(3S)-7-fluoro-3-methyl-2,3-dihydro-1,4-benzoxazine-4-carbonyl]-4H-1,4-benzoxazin-3-one
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C18H15FN2O4
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0434545
 Compound Info 
2-[(3S)-5,7-difluoro-4-(3-oxo-4H-1,4-benzoxazine-6-carbonyl)-2,3-dihydro-1,4-benzoxazin-3-yl]acetamide
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C19H15F2N3O5
  1
1
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS