| Compound ID |
Compound Name |
Compound Formula |
|
CP0421429
|
US10562853, Compound 3
Show/Hide
|
C23H26Cl2FN3O3
|
1
|
| 1 |
EC50 = 0.02512 nM
|
|
|
|
CP0479916
|
US10562853, Compound 52
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|
C22H26ClF2N3O2
|
1
|
| 1 |
EC50 = 0.08913 nM
|
|
|
|
CP0421428
|
US10562853, Compound 60
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|
C25H29ClF2N2O3
|
1
|
| 1 |
EC50 = 0.3236 nM
|
|
|
|
CP0421434
|
US10562853, Compound 6
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|
C22H25ClF2N2O3
|
1
|
| 1 |
EC50 = 0.3715 nM
|
|
|
|
CP0479949
|
US10562853, Compound 8
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|
C22H25ClF2N2O3
|
1
|
| 1 |
EC50 = 2.291 nM
|
|
|
|
CP0479920
|
US10562853, Compound 47
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|
C22H24ClF2N3O3
|
1
|
| 1 |
EC50 = 2.818 nM
|
|
|
|
CP0484979
|
US10562853, Compound 48
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|
C22H24ClF2N3O3
|
1
|
| 1 |
EC50 = 8.318 nM
|
|
|
|
CP0471680
|
US10562853, Compound 1
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|
C21H23ClF2N2O2
|
1
|
| 1 |
EC50 = 10.47 nM
|
|
|
|
CP0037227
|
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
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|
C16H25NO
|
1
|
| 1 |
EC50 = 14.45 nM
|
|
|
|
CP0432139
|
US10562853, Compound 62
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|
C21H22Cl2F2N2O2
|
1
|
| 1 |
EC50 = 17.38 nM
|
|
|
|
CP0032640
|
US10562853, Compound 18
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|
C20H22ClF2N3O2
|
1
|
| 1 |
EC50 = 20.89 nM
|
|
|
|
CP0479918
|
US10562853, Compound 61
Show/Hide
|
C21H22ClF3N2O2
|
1
|
| 1 |
EC50 = 24.55 nM
|
|
|
|
CP0421401
|
US10562853, Compound 36
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|
C19H21ClF2N4O2
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0479951
|
US10562853, Compound 5
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|
C21H22ClF3N2O2
|
1
|
| 1 |
EC50 = 34.67 nM
|
|
|
|
CP0421427
|
US10562853, Compound 63
Show/Hide
|
C22H25ClF2N2O2
|
1
|
| 1 |
EC50 = 53.7 nM
|
|
|
|
CP0471528
|
US10562853, Compound 45
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|
C23H28ClF2N3O2
|
1
|
| 1 |
EC50 = 60.26 nM
|
|
|
|
CP0421456
|
US10562853, Compound 64
Show/Hide
|
C21H22ClF3N2O2
|
1
|
| 1 |
EC50 = 87.1 nM
|
|
|
|
CP0466157
|
US10562853, Compound 55
Show/Hide
|
C21H24ClF2N3O
|
1
|
| 1 |
EC50 = 114.82 nM
|
|
|
|
CP0424643
|
US10562853, Compound 9
Show/Hide
|
C22H25Cl2FN2O3
|
1
|
| 1 |
EC50 = 123.03 nM
|
|
|
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
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|
C10H12N2O
|
1
|
| 1 |
EC50 = 128.82 nM
|
|
|
|
CP0507465
|
US10562853, Compound 19
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|
C20H22ClF2N3O2
|
1
|
| 1 |
EC50 = 134.9 nM
|
|
|
|
CP0479952
|
US10562853, Compound 51
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|
C22H26ClF2N3O2
|
1
|
| 1 |
EC50 = 162.18 nM
|
|
|
|
CP0424569
|
US10562853, Compound 74
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|
C20H22Cl2FN3O2
|
1
|
| 1 |
EC50 = 173.78 nM
|
|
|
|
CP0042717
|
(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
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|
C21H31N5O2
|
1
|
| 1 |
EC50 = 186.21 nM
|
|
|
|
CP0378668
|
(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyrimidin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
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|
C19H21ClF2N4O
|
1
|
| 1 |
EC50 = 194.98 nM
|
|
|
|
CP0479950
|
US10562853, Compound 4
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|
C21H22Cl2F2N2O2
|
1
|
| 1 |
EC50 = 223.87 nM
|
|
|
|
CP0421400
|
US10562853, Compound 54
Show/Hide
|
C20H23ClF2N4O
|
1
|
| 1 |
EC50 = 263.03 nM
|
|
|
|
CP0424570
|
US10562853, Compound 40
Show/Hide
|
C20H22ClF2N3OS
|
1
|
| 1 |
EC50 = 288.4 nM
|
|
|
|
CP0421399
|
US10562853, Compound 59
Show/Hide
|
C22H25ClF2N2O
|
1
|
| 1 |
EC50 = 446.68 nM
|
|
|
|
CP0421480
|
(3,4-dichlorophenyl)-[4-fluoro-4-[[2-(3-fluorophenoxy)ethylamino]methyl]piperidin-1-yl]methanone
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|
C21H22Cl2F2N2O2
|
1
|
| 1 |
EC50 = 616.6 nM
|
|
|
|
CP0471679
|
US10562853, Compound 46
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|
C22H22ClF5N2O2
|
1
|
| 1 |
EC50 = 724.44 nM
|
|
|
|
CP0479927
|
US10562853, Compound 65
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|
C21H22Cl2F2N2O2
|
1
|
| 1 |
EC50 = 977.24 nM
|
|
|
|
CP0448031
|
US10562853, Compound 10
Show/Hide
|
C22H25ClF2N2O3
|
1
|
| 1 |
EC50 = 1621.81 nM
|
|
|
|
CP0424571
|
US10562853, Compound 53
Show/Hide
|
C21H24ClF2N3O
|
1
|
| 1 |
EC50 = 1995.26 nM
|
|
|
|
CP0479919
|
US10562853, Compound 11
Show/Hide
|
C22H25Cl2FN2O3
|
1
|
| 1 |
EC50 = 2511.89 nM
|
|
|
|
CP0555328
|
US10562853, Compound 35
Show/Hide
|
C20H23ClF2N4O2
|
1
|
| 1 |
EC50 = 2754.23 nM
|
|
|
|
CP0546077
|
(3-chloro-4-fluorophenyl)-[4-fluoro-4-[(2-phenylsulfanylethylamino)methyl]piperidin-1-yl]methanone
Show/Hide
|
C21H23ClF2N2OS
|
1
|
| 1 |
EC50 = 3630.78 nM
|
|
|
