Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT01172 , Progesterone receptor
 Protein Info 
Gene Name PGR
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P06401
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT01172
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0168519
 Compound Info 
LEVONORGESTREL
   Show/Hide
C21H28O2
  1
1
EC50 = 1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849449
 Compound Info 
(R)-5-benzyl-3-((R)-1-(4-fluorophenyl)ethyl)-5-(5-morpholino-1H-benzo[d]imidazol-2-yl)oxazolidine-2,4-dione
   Show/Hide
C29H27FN4O4
  1
1
IC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849447
 Compound Info 
(R)-5-benzyl-5-(5-chloro-1H-benzo[d]imidazol-2-yl)-3-((R)-1-(4-fluorophenyl)ethyl)oxazolidine-2,4-dione
   Show/Hide
C25H19ClFN3O3
  1
1
IC50 = 2400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0861154
 Compound Info 
(R)-5-benzyl-3-((R)-1-(4-fluorophenyl)ethyl)-5-(5-(3-methylisoxazol-4-yl)-1H-benzo[d]imidazol-2-yl)oxazolidine-2,4-dione
   Show/Hide
C29H23FN4O4
  1
1
IC50 = 2800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0849448
 Compound Info 
(R)-5-(5-(1H-pyrazol-3-yl)-1H-benzo[d]imidazol-2-yl)-5-benzyl-3-((R)-1-(4-fluorophenyl)ethyl)oxazolidine-2,4-dione
   Show/Hide
C28H22FN5O3
  1
1
IC50 = 2900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0861144
 Compound Info 
(R)-5-benzyl-3-((R)-1-(4-fluorophenyl)ethyl)-5-(5-(pyridin-3-yl)-1H-benzo[d]imidazol-2-yl)oxazolidine-2,4-dione
   Show/Hide
C30H23FN4O3
  1
1
IC50 = 2900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0861152
 Compound Info 
(R)-5-benzyl-3-((R)-1-(4-fluorophenyl)ethyl)-5-(5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)oxazolidine-2,4-dione
   Show/Hide
C26H19F4N3O3
  1
1
IC50 = 3200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0851122
 Compound Info 
N-(2-((R)-5-benzyl-3-((R)-1-(4-fluorophenyl)ethyl)-2,4-dioxooxazolidin-5-yl)-1H-benzo[d]imidazol-5-yl)methanesulfonamide
   Show/Hide
C26H23FN4O5S
  1
1
IC50 = 4900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0848708
 Compound Info 
N-(2-((R)-5-benzyl-3-((R)-1-(4-fluorophenyl)ethyl)-2,4-dioxooxazolidin-5-yl)-1H-benzo[d]imidazol-4-yl)methanesulfonamide
   Show/Hide
C26H23FN4O5S
  1
1
IC50 = 8200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS