Compound ID |
Compound Name |
Compound Formula |
CP0006292
|
(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2,4,6-triene-5,14-diol
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|
C18H24O2
|
3
|
1 |
EC50 = 0.019 nM
|
|
|
2 |
EC50 = 2.773 nM
|
|
|
3 |
IC50 = 21.04 nM
|
|
|
CP0080858
|
1,3-Diethyl-2-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C19H20O2
|
1
|
1 |
EC50 = 0.059 nM
|
|
|
CP0062959
|
PROPYLPYRAZOLETRIOL
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|
C24H22N2O3
|
1
|
1 |
EC50 = 0.1 nM
|
|
|
CP0121204
|
4-[3,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-fluorophenol
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|
C25H22FNO3
|
1
|
1 |
EC50 = 0.12 nM
|
|
|
CP0335581
|
4-[4,5-bis(2-fluoro-4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-fluorophenol
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|
C25H20F3NO3
|
1
|
1 |
EC50 = 0.2 nM
|
|
|
CP0138900
|
3-fluoro-4-[5-(2-fluoro-4-hydroxyphenyl)-4-(4-hydroxyphenyl)-1-propylpyrrol-2-yl]phenol
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|
C25H21F2NO3
|
1
|
1 |
EC50 = 0.27 nM
|
|
|
CP0254889
|
1-Ethyl-2-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C17H16O2
|
1
|
1 |
EC50 = 0.31 nM
|
|
|
CP0138898
|
4-[3,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-chlorophenol
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|
C25H22ClNO3
|
1
|
1 |
EC50 = 0.31 nM
|
|
|
CP0243845
|
4-[4,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]phenol
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|
C25H23NO3
|
1
|
1 |
EC50 = 0.4 nM
|
|
|
CP0243842
|
4-[4,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-fluorophenol
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|
C25H22FNO3
|
1
|
1 |
EC50 = 0.67 nM
|
|
|
CP0259219
|
4-[2,5-bis(4-hydroxyphenyl)-1-propylpyrrol-3-yl]-3-fluorophenol
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|
C25H22FNO3
|
1
|
1 |
EC50 = 0.84 nM
|
|
|
CP0138897
|
4-[1,5-bis(4-hydroxyphenyl)-4-propylpyrrol-3-yl]phenol
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|
C25H23NO3
|
1
|
1 |
EC50 = 1.6 nM
|
|
|
CP0269771
|
1-(4-Fluoro-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C21H15FO2
|
1
|
1 |
EC50 = 3.9 nM
|
|
|
CP0171370
|
2-(4-Hydroxy-phenyl)-1-phenyl-3H-inden-5-ol
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|
C21H16O2
|
1
|
1 |
EC50 = 4.3 nM
|
|
|
CP0319985
|
1-(4-Amino-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C21H17NO2
|
1
|
1 |
EC50 = 6.7 nM
|
|
|
CP0179169
|
1,2-Bis-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C21H16O3
|
1
|
1 |
EC50 = 7 nM
|
|
|
CP0319986
|
1-Benzyl-2-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C22H18O2
|
1
|
1 |
EC50 = 14 nM
|
|
|
CP0166061
|
2-(4-Hydroxy-phenyl)-1-(4-trifluoromethyl-phenyl)-3H-inden-5-ol
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|
C22H15F3O2
|
1
|
1 |
EC50 = 15 nM
|
|
|
CP0243840
|
3-fluoro-4-[5-(2-fluoro-4-hydroxyphenyl)-4-(4-hydroxyphenyl)-1-methylpyrrol-2-yl]phenol
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|
C23H17F2NO3
|
1
|
1 |
EC50 = 15 nM
|
|
|
CP0243841
|
4-[3,5-bis(4-hydroxyphenyl)-1-methylpyrrol-2-yl]-3-chlorophenol
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|
C23H18ClNO3
|
1
|
1 |
EC50 = 16 nM
|
|
|
CP0220902
|
1-(4-Chloro-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C21H15ClO2
|
1
|
1 |
EC50 = 17 nM
|
|
|
CP0273667
|
2-(4-Hydroxy-phenyl)-1-p-tolyl-3H-inden-5-ol
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|
C22H18O2
|
1
|
1 |
EC50 = 17 nM
|
|
|
CP0243843
|
4-[4,5-bis(4-hydroxyphenyl)-1-methylpyrrol-2-yl]-3-fluorophenol
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|
C23H18FNO3
|
1
|
1 |
EC50 = 24 nM
|
|
|
CP0374954
|
(8R,9S,13S,14S,17R)-17-[(E)-4,4,5,5,6,6,6-heptafluorohex-1-enyl]-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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|
C24H27F7O2
|
2
|
1 |
EC50 = 35.48 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0138901
|
4-[4,5-bis(4-hydroxyphenyl)-1-propylpyrrol-2-yl]-3-chlorophenol
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|
C25H22ClNO3
|
1
|
1 |
EC50 = 47 nM
|
|
|
CP0335580
|
4-[3,5-bis(4-hydroxyphenyl)-1-methylpyrrol-2-yl]-3-fluorophenol
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|
C23H18FNO3
|
1
|
1 |
EC50 = 60 nM
|
|
|
CP0076766
|
3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1-carboxylic acid [4-(2-piperidin-1-yl-ethoxy)-phenyl]-amide
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|
C31H34N2O4
|
1
|
1 |
EC50 = 100 nM
|
|
|
CP0335571
|
4-[4,5-bis(4-hydroxyphenyl)-1-methylpyrrol-2-yl]-3-chlorophenol
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|
C23H18ClNO3
|
1
|
1 |
EC50 = 100 nM
|
|
|
CP0276695
|
1-(4-Bromomethyl-phenyl)-2-(4-hydroxy-phenyl)-3H-inden-5-ol
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|
C22H17BrO2
|
1
|
1 |
EC50 = 109 nM
|
|
|
CP0280338
|
3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide
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|
C28H30N2O4
|
1
|
1 |
EC50 = 152 nM
|
|
|
CP0076765
|
3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1-carboxylic acid
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|
C18H16O4
|
1
|
1 |
EC50 = 158 nM
|
|
|
CP0427567
|
(8R,9S,13S,14S,17R)-13-methyl-17-[(E)-5,6,6,6-tetrafluoro-5-(trifluoromethyl)hex-2-enyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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|
C25H29F7O2
|
2
|
1 |
EC50 = 402.72 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0319983
|
3-Ethyl-6-hydroxy-2-(4-hydroxy-phenyl)-1H-indene-1-carboxylic acid (4-hydroxy-phenyl)-amide
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|
C24H21NO4
|
1
|
1 |
EC50 = 427 nM
|
|
|
CP0387718
|
(8R,9S,13S,14S,17R)-17-[(E)-5,5,6,6,7,7,7-heptafluorohept-2-enyl]-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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|
C25H29F7O2
|
2
|
1 |
EC50 = 485.29 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0386424
|
(8R,9S,13S,14S,17R)-13-methyl-17-[(E)-5,5,6,6,7,7,8,8,9,9,10,10,10-tridecafluorodec-2-enyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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|
C28H29F13O2
|
2
|
1 |
EC50 = 1028.02 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0380441
|
(8R,9S,13S,14S,17R)-17-[(E)-5,5,6,6,7,7,7-heptafluorohept-2-enyl]-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
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|
C26H31F7O2
|
2
|
1 |
EC50 = 1655.77 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0372764
|
(8R,9S,13S,14S,17R)-13-methyl-17-[(E)-4,4,5,5,6,6,7,7,8,8,9,9,9-tridecafluoronon-1-enyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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|
C27H27F13O2
|
2
|
1 |
EC50 = 2079.7 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0375884
|
(8R,9S,13S,14S,17R)-17-[(E)-4,4,5,5,6,6,6-heptafluorohex-1-enyl]-3-methoxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
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|
C25H29F7O2
|
2
|
1 |
EC50 = 4027.17 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0375887
|
(8R,9S,13S,14S,17R)-13-methyl-17-[(E)-4,5,5,5-tetrafluoro-4-(trifluoromethyl)pent-1-enyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
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|
C24H27F7O2
|
2
|
1 |
EC50 = 9954.05 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0380442
|
(8R,9S,13S,14S,17R)-3-methoxy-13-methyl-17-[(E)-5,5,6,6,7,7,8,8,9,9,10,10,10-tridecafluorodec-2-enyl]-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol
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|
C29H31F13O2
|
2
|
1 |
EC50 < 15848.93 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0846678
|
1'-(E)-[(3-Methoxy-17-(4',4',5',5',6',6',7',7',8',8',9',9',9'-tridecafluoronon-1'-en-1'-yl)estra-17beta-ol]
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|
C28H29F13O2
|
2
|
1 |
EC50 < 15848.93 nM
|
|
|
2 |
IC50 < 15848.93 nM
|
|
|
CP0240380
|
4-[(E)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
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|
C26H29NO2
|
1
|
1 |
IC50 = 2.28 nM
|
|
|
CP0045086
|
4-Hydroxytamoxifen
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|
C26H29NO2
|
1
|
1 |
IC50 = 2.3 nM
|
|
|
CP0943751
|
2-(3-(4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)ethanaminium 2,2,2-trifluoroacetate
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|
C29H29F3N2O4
|
1
|
1 |
IC50 = 5.3 nM
|
|
|
CP0317701
|
(E)-N-(2-aminoethyl)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enamide;2,2,2-trifluoroacetic acid
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|
C33H31F9N2O8
|
1
|
1 |
IC50 = 5.33 nM
|
|
|
CP0833947
|
3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(5-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)pentyl)acrylamide
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|
C41H44N4O4
|
1
|
1 |
IC50 = 9.2 nM
|
|
|
CP0835418
|
3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(6-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)hexyl)acrylamide
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|
C42H46N4O4
|
1
|
1 |
IC50 = 9.4 nM
|
|
|
CP0776597
|
3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(2-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)ethyl)acrylamide
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|
C38H38N4O4
|
1
|
1 |
IC50 = 9.7 nM
|
|
|
CP0950473
|
N-[4-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)butyl]-8-(4-oxo-2-thioxodihydroquinazolin-3-yl)octanamide
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|
C45H50N4O4S
|
1
|
1 |
IC50 = 18.5 nM
|
|
|
CP0944381
|
(E/Z)-N-[6-(3-(5-Hydroxy-1H-benzo[d]imidazol-2-yl)-propanamido)hexyl]-3-[4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl]acrylamide
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|
C41H44N4O4
|
1
|
1 |
IC50 = 20 nM
|
|
|
CP0835412
|
3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(3-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)propyl)acrylamide
Show/Hide
|
C39H40N4O4
|
1
|
1 |
IC50 = 21.5 nM
|
|
|
CP0960446
|
N-(2-(3-(5-Hydroxy-1H-benzo(d)imidazol-2-yl)-propanamido)ethyl)-3-(4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamide
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|
C37H36N4O4
|
1
|
1 |
IC50 = 26 nM
|
|
|
CP0835404
|
N-(3-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)propyl)-4-(4-oxo-2-thioxodihydroquinazolin-3-yl)butanamide
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|
C40H40N4O4S
|
1
|
1 |
IC50 = 30.2 nM
|
|
|
CP0835419
|
(E)-N-[5-(3-(5-Hydroxy-1H-benzo[d]imidazol-2-yl)-propanamido)pentyl]-3-[4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl]acrylamide
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|
C40H42N4O4
|
1
|
1 |
IC50 = 30.9 nM
|
|
|
CP0835416
|
3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)-N-(4-(3-(5-methoxy-1H-benzo(d)imidazol-2-yl)-propanamido)butyl)acrylamide
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|
C40H42N4O4
|
1
|
1 |
IC50 = 34.5 nM
|
|
|
CP0557200
|
(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[5-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]pentyl]prop-2-enamide
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|
C49H54N2O4
|
1
|
1 |
IC50 = 73 nM
|
|
|
CP0833945
|
N-[3-(3-(5-Hydroxy-1H-benzo[d]imidazol-2-yl)-propanamido)propyl]-3-[4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl]acrylamide
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|
C38H38N4O4
|
1
|
1 |
IC50 = 80.8 nM
|
|
|
CP0317700
|
(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[4-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]butyl]prop-2-enamide
Show/Hide
|
C48H52N2O4
|
1
|
1 |
IC50 = 88.3 nM
|
|
|
CP0960445
|
N-[3-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)propyl]-4-[4-(4-(4-oxo-2-thioxodihydroquinazolin-3-yl)butanoyl)piperazin-1-yl]benzamide
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|
C51H52N6O5S
|
1
|
1 |
IC50 = 104 nM
|
|
|
CP0770059
|
N-(4-(3-(5-Hydroxy-1H-benzo(d)imidazol-2-yl)-propanamido)butyl)-3-(4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamide
Show/Hide
|
C39H40N4O4
|
1
|
1 |
IC50 = 107 nM
|
|
|
CP0240379
|
(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[2-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]ethyl]prop-2-enamide
Show/Hide
|
C46H48N2O4
|
1
|
1 |
IC50 = 131 nM
|
|
|
CP0363564
|
(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[3-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]propyl]prop-2-enamide
Show/Hide
|
C53H50N2O4
|
1
|
1 |
IC50 = 136 nM
|
|
|
CP0240381
|
(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[5-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]pentyl]prop-2-enamide
Show/Hide
|
C55H54N2O4
|
1
|
1 |
IC50 = 160 nM
|
|
|
CP0040596
|
(E)-3-[4-[(E)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoic acid
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|
C25H22O3
|
1
|
1 |
IC50 = 238 nM
|
|
|
CP0690577
|
(E)-3-(4-((E/Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylic acid
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|
C25H22O3
|
1
|
1 |
IC50 = 238 nM
|
|
|
CP0240382
|
(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[2-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]ethyl]prop-2-enamide
Show/Hide
|
C52H48N2O4
|
1
|
1 |
IC50 = 260 nM
|
|
|
CP0264515
|
(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]-N-[4-[[(E)-3-[4-[(Z)-1-(4-hydroxyphenyl)-2-phenylbut-1-enyl]phenyl]prop-2-enoyl]amino]butyl]prop-2-enamide
Show/Hide
|
C54H52N2O4
|
1
|
1 |
IC50 = 290 nM
|
|
|
CP0240378
|
(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]-N-[3-[[(E)-3-[4-[cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enoyl]amino]propyl]prop-2-enamide
Show/Hide
|
C47H50N2O4
|
1
|
1 |
IC50 = 565 nM
|
|
|
CP0943750
|
N-(3-(3-(4-((E/Z)-1-(4-Hydroxyphenyl)-2-phenylbut-1-enyl)phenyl)acrylamido)propyl)-4-(4-(8-(4-oxo-2-thioxodihydroquinazolin-3-yl)octanoyl)piperazin-1-yl)benzamide
Show/Hide
|
C55H60N6O5S
|
1
|
1 |
IC50 = 914 nM
|
|
|