Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT00903 , C-C chemokine receptor type 5
 Protein Info 
Gene Name CCR5
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P51681
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT00903
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0355426
 Compound Info 
2-amino-6-[(2,3-dichlorophenyl)methyl]-5-propan-2-yl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
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C15H15Cl2N5O
  5
1
EC50 = 4.467 nM
 Bioactivity Info 
   TI
   LI
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2
EC50 = 5 nM
 Bioactivity Info 
   TI
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3
EC50 = 7.244 nM
 Bioactivity Info 
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4
EC50 = 8 nM
 Bioactivity Info 
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5
EC50 = 9 nM
 Bioactivity Info 
   TI
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CP0382814
 Compound Info 
2-amino-6-[(3-bromo-4-chlorophenyl)methyl]-5-propan-2-yl-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
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C15H15BrClN5O
  6
1
EC50 = 5 nM
 Bioactivity Info 
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2
EC50 = 5.012 nM
 Bioactivity Info 
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3
EC50 = 6 nM
 Bioactivity Info 
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4
EC50 = 6.166 nM
 Bioactivity Info 
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5
EC50 = 8.913 nM
 Bioactivity Info 
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6
EC50 = 9 nM
 Bioactivity Info 
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CP0666580
 Compound Info 
Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium chloride(TAK-779)
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C33H39ClN2O2
  1
1
IC50 = 6 nM
 Bioactivity Info 
   TI
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CP0533791
 Compound Info 
(2R)-3-acetyl-1-(4-chloro-2-fluorophenyl)-2-cyclohexyl-4-hydroxy-2H-pyrrol-5-one
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C18H19ClFNO3
  1
1
IC50 = 703 nM
 Bioactivity Info 
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