Brief Information of the Cell Line and Protein
Cell Line ID: CL000043 , U2OS
 Cell Line Info 
Synonyms
U-2 OS
U-2OS
U-2-OS
U2-OS
U20-S
U20S
2T
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0042
Protein ID: PT05484 , C-C chemokine receptor type 10
 Protein Info 
Gene Name CCR10
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P46092
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000043
 Cell Line Info 
 Protein ID: PT05484
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0670595
 Compound Info 
Brintonamide D
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C48H66N6O10
  1
1
IC50 = 440 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0899057
 Compound Info 
Brintonamide E
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C48H66N6O10
  1
1
IC50 = 2710 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0854392
 Compound Info 
(S)-methyl 1-((6S,9S,12R)-12-benzyl-6-isobutyl-5,9,11-trimethyl-1-((S)-1-((2R,3S)-3-methyl-2-(3-phenylpropanoyloxy)pentanoyl)pyrrolidin-2-yl)-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecane)pyrrolidine-2-carboxylate
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C48H68N6O10
  1
1
IC50 = 3140 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0219007
 Compound Info 
methyl (2S)-1-[(2R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2R,3S)-2-hydroxy-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]-methylamino]-4-methylpentanoyl]amino]propanoyl]-methylamino]-3-phenylpropanoyl]pyrrolidine-2-carboxylate
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C39H60N6O9
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0762370
 Compound Info 
Brintonamide B
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C38H58N6O9
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0762384
 Compound Info 
Brintonamide C
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C50H73N7O10
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0883486
 Compound Info 
(S)-methyl 1-((6S,9S,12R)-12-benzyl-6-isobutyl-5,9,11-trimethyl-1-((S)-1-((2R,3S)-3-methyl-2-(3-phenylpropioloyloxy)pentanoyl)pyrrolidin-2-yl)-1,4,7,10-tetraoxo-2,5,8,11-tetraazatridecane)pyrrolidine-2-carboxylate
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C48H64N6O10
  1
1
IC50 > 20000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS