General Information of the Protein
Protein ID
PT03450
Protein Name
Taste receptor type 2 member 14
Secondarily
Protein Name
Taste receptor family B member 1
Gene Name
TAS2R14
Sequence
MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
    Show/Hide
Organism
Homo sapiens, Human
Protein Classification
Membrane receptor
>
Taste family G protein-coupled receptor
>
Taste receptor (taste family GPCR)
Function
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
    Show/Hide
Uniprot ID
Primary ID:
Q9NYV8

Secondarily ID:
Q645X3
    Show/Hide
HGNC ID
HGNC:14920
Subcellular Location
Membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000043 , U2OS
Compound ID Compound Name Compound Formula
CP0006743
4-methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
   Show/Hide
C16H19NO3S
 2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
IC50 > 39810.72 nM
   TI
   LI
   LO
   TS