General Information of the Compound
Compound ID
CP0496525
Compound Name
3-Dipropylamino-1-(1,2,3,4-tetrahydro-phenanthren-9-yl)-propan-1-ol
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Structure
Formula
C23H33NO
Molecular Weight
339.523
Canonical SMILES
CCCN(CCC)CCC(O)c1cc2CCCCc2c2ccccc12
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InChI
InChI=1S/C23H33NO/c1-3-14-24(15-4-2)16-13-23(25)22-17-18-9-5-6-10-19(18)20-11-7-8-12-21(20)22/h7-8,11-12,17,23,25H,3-6,9-10,13-16H2,1-2H3
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InChIKey
XASXMEKXZPGFQK-UHFFFAOYSA-N
Physicochemical Property
logP
5.2641
Rotatable Bonds
8
Heavy Atom Count
25
Polar Areas
23.47
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 408574
SID: 15446634
ChEMBL ID
CHEMBL138570
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1258 nM
   TI
   LI
   LO
   TS