General Information of the Compound
Compound ID
CP0521742
Compound Name
N-[4-[4-(5-methoxy-1,2-benzoxazol-3-yl)piperazin-1-yl]butyl]-3-(5-methyl-1,2,4-oxadiazol-3-yl)benzamide
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Structure
Formula
C26H30N6O4
Molecular Weight
490.564
Canonical SMILES
COc1ccc2onc(N3CCN(CCCCNC(=O)c4cccc(c4)-c4noc(C)n4)CC3)c2c1
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InChI
InChI=1S/C26H30N6O4/c1-18-28-24(29-35-18)19-6-5-7-20(16-19)26(33)27-10-3-4-11-31-12-14-32(15-13-31)25-22-17-21(34-2)8-9-23(22)36-30-25/h5-9,16-17H,3-4,10-15H2,1-2H3,(H,27,33)
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InChIKey
ZPVPYUKSPMCCQN-UHFFFAOYSA-N
Physicochemical Property
logP
3.52702
Rotatable Bonds
9
Heavy Atom Count
36
Polar Areas
109.76
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
9
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11691676
SID: 16796024
ChEMBL ID
CHEMBL426834
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1285 nM
   TI
   LI
   LO
   TS