General Information of the Compound
Compound ID
CP0885952
Compound Name
3-(3-Iodo-4,5-dimethoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide oxalic acid
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Structure
Formula
C28H36IN3O8
Molecular Weight
669.513
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)/C=C/c2cc(I)c(OC)c(OC)c2)CC1.O=C(O)C(=O)O
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InChI
InChI=1S/C26H34IN3O4.C2H2O4/c1-32-23-9-5-4-8-22(23)30-16-14-29(15-17-30)13-7-6-12-28-25(31)11-10-20-18-21(27)26(34-3)24(19-20)33-2;3-1(4)2(5)6/h4-5,8-11,18-19H,6-7,12-17H2,1-3H3,(H,28,31);(H,3,4)(H,5,6)/b11-10+;
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InChIKey
FGFFJOHLMOLVEC-ASTDGNLGSA-N
Physicochemical Property
logP
3.2044
Rotatable Bonds
11
Heavy Atom Count
40
Polar Areas
137.87
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
8
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44350773
ChEMBL ID
CHEMBL127923
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 38.5 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 14.9 nM
   TI
   LI
   LO
   TS