General Information of the Compound
Compound ID
CP0555166
Compound Name
N-[4-[(3aS,9bS)-7-hydroxy-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-3-yl]butyl]-4-phenylbenzamide
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Structure
Formula
C29H32N2O2
Molecular Weight
440.587
Canonical SMILES
Oc1ccc2[C@@H]3CCN(CCCCNC(=O)c4ccc(cc4)-c4ccccc4)[C@H]3CCc2c1
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InChI
InChI=1S/C29H32N2O2/c32-25-13-14-26-24(20-25)12-15-28-27(26)16-19-31(28)18-5-4-17-30-29(33)23-10-8-22(9-11-23)21-6-2-1-3-7-21/h1-3,6-11,13-14,20,27-28,32H,4-5,12,15-19H2,(H,30,33)/t27-,28-/m0/s1
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InChIKey
GFWJJPMDPCQZBK-NSOVKSMOSA-N
Physicochemical Property
logP
5.3735
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
52.57
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44329130
ChEMBL ID
CHEMBL97856
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 12.59 nM
   TI
   LI
   LO
   TS