Brief Information of the Compound and Protein
Compound Name
Cariprazine
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PubChem ID
SID: 24759793
Canonical SMILES
CN(C)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc(Cl)c2Cl)CC1
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Compound Formula C21H32Cl2N4O
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  3
1
Ki = 0.085 nM
   TI
   LI
   LO
   TS
2
Ki = 0.096 nM
   TI
   LI
   LO
   TS
3
Ki = 0.27 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.085 nM