General Information of the Compound
Compound ID
CP0399806
Compound Name
4-phenyl-N-[4-[propyl(4,5,6,7-tetrahydro-1H-indazol-5-yl)amino]butyl]benzamide
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Structure
Formula
C27H34N4O
Molecular Weight
430.596
Canonical SMILES
CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2n[nH]cc2C1
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InChI
InChI=1S/C27H34N4O/c1-2-17-31(25-14-15-26-24(19-25)20-29-30-26)18-7-6-16-28-27(32)23-12-10-22(11-13-23)21-8-4-3-5-9-21/h3-5,8-13,20,25H,2,6-7,14-19H2,1H3,(H,28,32)(H,29,30)
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InChIKey
KHDCGMWSBNKZBB-UHFFFAOYSA-N
Physicochemical Property
logP
4.8562
Rotatable Bonds
10
Heavy Atom Count
32
Polar Areas
61.02
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44324986
ChEMBL ID
CHEMBL91156
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.162 nM
   TI
   LI
   LO
   TS