General Information of the Compound
Compound ID
CP0858090
Compound Name
1-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-phenyl-pyrrole-2,5-dione oxalic acid
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Structure
Formula
C27H31N3O7
Molecular Weight
509.559
Canonical SMILES
COc1ccccc1N1CCN(CCCCN2C(=O)C=C(c3ccccc3)C2=O)CC1.O=C(O)C(=O)O
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InChI
InChI=1S/C25H29N3O3.C2H2O4/c1-31-23-12-6-5-11-22(23)27-17-15-26(16-18-27)13-7-8-14-28-24(29)19-21(25(28)30)20-9-3-2-4-10-20;3-1(4)2(5)6/h2-6,9-12,19H,7-8,13-18H2,1H3;(H,3,4)(H,5,6)
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InChIKey
IDLLRKLCRRBGTJ-UHFFFAOYSA-N
Physicochemical Property
logP
2.2054
Rotatable Bonds
8
Heavy Atom Count
37
Polar Areas
127.69
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
7
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44350774
ChEMBL ID
CHEMBL129502
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 330 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 320 nM
   TI
   LI
   LO
   TS