General Information of the Compound
Compound ID
CP0402038
Compound Name
3-[(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-(3-morpholin-4-yl-propyl)-amino]-propionitrile
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Structure
Formula
C19H24N4O3
Molecular Weight
356.426
Canonical SMILES
O=C1N(CN(CCCN2CCOCC2)CCC#N)C(=O)c2ccccc12
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InChI
InChI=1S/C19H24N4O3/c20-7-3-8-22(10-4-9-21-11-13-26-14-12-21)15-23-18(24)16-5-1-2-6-17(16)19(23)25/h1-2,5-6H,3-4,8-15H2
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InChIKey
YWAYIZIRYOLBEC-UHFFFAOYSA-N
Physicochemical Property
logP
1.17808
Rotatable Bonds
8
Heavy Atom Count
26
Polar Areas
76.88
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
6
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 304988
ChEMBL ID
CHEMBL343536
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 10000 nM
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   LI
   LO
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