General Information of the Compound
Compound ID
CP0503881
Compound Name
N-[4-[4-(N-acetyl-2-methoxyanilino)piperidin-1-yl]butyl]naphthalene-2-carboxamide
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Structure
Formula
C29H35N3O3
Molecular Weight
473.617
Canonical SMILES
COc1ccccc1N(C1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1)C(C)=O
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InChI
InChI=1S/C29H35N3O3/c1-22(33)32(27-11-5-6-12-28(27)35-2)26-15-19-31(20-16-26)18-8-7-17-30-29(34)25-14-13-23-9-3-4-10-24(23)21-25/h3-6,9-14,21,26H,7-8,15-20H2,1-2H3,(H,30,34)
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InChIKey
BWJWQRCGVCCLIP-UHFFFAOYSA-N
Physicochemical Property
logP
4.8759
Rotatable Bonds
9
Heavy Atom Count
35
Polar Areas
61.88
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44436767
ChEMBL ID
CHEMBL238875
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 13350 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2340 nM
   TI
   LI
   LO
   TS