General Information of the Compound
Compound ID
CP0485814
Compound Name
N-[4-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]butyl]cyclohexanecarboxamide
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Structure
Formula
C28H38ClN3O
Molecular Weight
468.085
Canonical SMILES
Clc1ccc(cc1)C(N1CCN(CCCCNC(=O)C2CCCCC2)CC1)c1ccccc1
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InChI
InChI=1S/C28H38ClN3O/c29-26-15-13-24(14-16-26)27(23-9-3-1-4-10-23)32-21-19-31(20-22-32)18-8-7-17-30-28(33)25-11-5-2-6-12-25/h1,3-4,9-10,13-16,25,27H,2,5-8,11-12,17-22H2,(H,30,33)
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InChIKey
BYOXBMSRXGFRQY-UHFFFAOYSA-N
Physicochemical Property
logP
5.5237
Rotatable Bonds
9
Heavy Atom Count
33
Polar Areas
35.58
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44436729
ChEMBL ID
CHEMBL239539
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 189 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 12.3 nM
   TI
   LI
   LO
   TS