General Information of the Compound
Compound ID
CP0541163
Compound Name
N-[2-[4-(1H-indol-2-ylmethyl)piperazin-1-yl]ethyl]-N-[(4-methoxyphenyl)methyl]propan-1-amine
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Structure
Formula
C26H36N4O
Molecular Weight
420.601
Canonical SMILES
CCCN(CCN1CCN(Cc2cc3ccccc3[nH]2)CC1)Cc1ccc(OC)cc1
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InChI
InChI=1S/C26H36N4O/c1-3-12-29(20-22-8-10-25(31-2)11-9-22)16-13-28-14-17-30(18-15-28)21-24-19-23-6-4-5-7-26(23)27-24/h4-11,19,27H,3,12-18,20-21H2,1-2H3
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InChIKey
WMJUHVXPQPZNMA-UHFFFAOYSA-N
Physicochemical Property
logP
4.2063
Rotatable Bonds
10
Heavy Atom Count
31
Polar Areas
34.74
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 122191610
ChEMBL ID
CHEMBL3622102
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 4100 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 4600 nM
   TI
   LI
   LO
   TS