General Information of the Compound
Compound ID
CP0515780
Compound Name
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3-benzodioxole-5-carboxamide
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Structure
Formula
C23H29N3O4
Molecular Weight
411.502
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc3OCOc3c2)CC1
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InChI
InChI=1S/C23H29N3O4/c1-28-20-7-3-2-6-19(20)26-14-12-25(13-15-26)11-5-4-10-24-23(27)18-8-9-21-22(16-18)30-17-29-21/h2-3,6-9,16H,4-5,10-15,17H2,1H3,(H,24,27)
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InChIKey
UBPODDPFCZVNDC-UHFFFAOYSA-N
Physicochemical Property
logP
2.7561
Rotatable Bonds
8
Heavy Atom Count
30
Polar Areas
63.27
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11603959
SID: 16706727
ChEMBL ID
CHEMBL201551
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Ki = 86.2 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 14.7 nM
   TI
   LI
   LO
   TS