General Information of the Compound
Compound ID
CP0071305
Compound Name
1-(3-chlorophenyl)-3-[2-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]ethyl]imidazolidin-2-one
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Structure
Formula
C22H28ClN3O3
Molecular Weight
417.937
Canonical SMILES
COc1ccc(CCN(C)CCN2CCN(C2=O)c2cccc(Cl)c2)cc1OC
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InChI
InChI=1S/C22H28ClN3O3/c1-24(10-9-17-7-8-20(28-2)21(15-17)29-3)11-12-25-13-14-26(22(25)27)19-6-4-5-18(23)16-19/h4-8,15-16H,9-14H2,1-3H3
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InChIKey
IAUZWUKARUVEJL-UHFFFAOYSA-N
Physicochemical Property
logP
3.7737
Rotatable Bonds
9
Heavy Atom Count
29
Polar Areas
45.25
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45271753
ChEMBL ID
CHEMBL554693
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 100 nM
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 125.89 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 125.89 nM