General Information of the Compound
Compound ID
CP0505180
Compound Name
(3-{4-[1-(6-{2-[4-(3-Diethylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-hexyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
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Structure
Formula
C46H60N6O2
Molecular Weight
729.026
Canonical SMILES
CCN(CC)CCCOc1ccc(cc1)-c1nc2ccccc2n1CCCCCCn1c(nc2ccccc12)-c1ccc(OCCCN(CC)CC)cc1
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InChI
InChI=1S/C46H60N6O2/c1-5-49(6-2)31-17-35-53-39-27-23-37(24-28-39)45-47-41-19-11-13-21-43(41)51(45)33-15-9-10-16-34-52-44-22-14-12-20-42(44)48-46(52)38-25-29-40(30-26-38)54-36-18-32-50(7-3)8-4/h11-14,19-30H,5-10,15-18,31-36H2,1-4H3
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InChIKey
CHBCJGRXRVEKLM-UHFFFAOYSA-N
Physicochemical Property
logP
10.202
Rotatable Bonds
23
Heavy Atom Count
54
Polar Areas
60.58
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Complexity
54

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44319569
ChEMBL ID
CHEMBL313257
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1750 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 131 nM
   TI
   LI
   LO
   TS