General Information of the Compound
Compound ID
CP0502038
Compound Name
4-(4-aminophenyl)-N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]benzamide
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Structure
Formula
C28H34N4O2
Molecular Weight
458.606
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccc(N)cc2)CC1
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InChI
InChI=1S/C28H34N4O2/c1-34-27-7-3-2-6-26(27)32-20-18-31(19-21-32)17-5-4-16-30-28(33)24-10-8-22(9-11-24)23-12-14-25(29)15-13-23/h2-3,6-15H,4-5,16-21,29H2,1H3,(H,30,33)
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InChIKey
YECOTWMMKZQQAE-UHFFFAOYSA-N
Physicochemical Property
logP
4.2766
Rotatable Bonds
9
Heavy Atom Count
34
Polar Areas
70.83
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11271099
SID: 16357264
ChEMBL ID
CHEMBL73665
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.1995 nM
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   LI
   LO
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