General Information of the Compound
Compound ID
CP0426890
Compound Name
N-[4-(4-benzhydryl-1,4-diazepan-1-yl)butyl]-1-benzothiophene-2-carboxamide
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Structure
Formula
C31H35N3OS
Molecular Weight
497.708
Canonical SMILES
O=C(NCCCCN1CCCN(CC1)C(c1ccccc1)c1ccccc1)c1cc2ccccc2s1
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InChI
InChI=1S/C31H35N3OS/c35-31(29-24-27-16-7-8-17-28(27)36-29)32-18-9-10-19-33-20-11-21-34(23-22-33)30(25-12-3-1-4-13-25)26-14-5-2-6-15-26/h1-8,12-17,24,30H,9-11,18-23H2,(H,32,35)
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InChIKey
ORDQHUBWYZCTMA-UHFFFAOYSA-N
Physicochemical Property
logP
6.2086
Rotatable Bonds
9
Heavy Atom Count
36
Polar Areas
35.58
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44436732
ChEMBL ID
CHEMBL401224
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 633 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 36.9 nM
   TI
   LI
   LO
   TS