General Information of the Compound
Compound ID
CP0479814
Compound Name
CHEMBL2113363
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Formula
C30H37ClFN3O3S
Molecular Weight
574.162
Canonical SMILES
Cl.Cc1ccc2c(ccc(F)c2n1)C(=O)N[C@H]1CC[C@H](CCN2CCc3ccc(cc3CC2)S(C)(=O)=O)CC1
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InChI
InChI=1S/C30H36FN3O3S.ClH/c1-20-3-10-26-27(11-12-28(31)29(26)32-20)30(35)33-24-7-4-21(5-8-24)13-16-34-17-14-22-6-9-25(38(2,36)37)19-23(22)15-18-34;/h3,6,9-12,19,21,24H,4-5,7-8,13-18H2,1-2H3,(H,33,35);1H/t21-,24-;
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InChIKey
PUBSQJWAOGDYQL-XDMBHIPYSA-N
Physicochemical Property
logP
5.28712
Rotatable Bonds
6
Heavy Atom Count
39
Polar Areas
79.37
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL2113363
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 794.33 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.162 nM
   TI
   LI
   LO
   TS