General Information of the Compound
Compound ID
CP0461112
Compound Name
3,5-dichloro-2-hydroxy-6-methoxy-N-[2-(4-phenylpiperazin-1-yl)ethyl]benzamide
    Show/Hide
Structure
Formula
C20H23Cl2N3O3
Molecular Weight
424.328
Canonical SMILES
COc1c(Cl)cc(Cl)c(O)c1C(=O)NCCN1CCN(CC1)c1ccccc1
    Show/Hide
InChI
InChI=1S/C20H23Cl2N3O3/c1-28-19-16(22)13-15(21)18(26)17(19)20(27)23-7-8-24-9-11-25(12-10-24)14-5-3-2-4-6-14/h2-6,13,26H,7-12H2,1H3,(H,23,27)
    Show/Hide
InChIKey
KEPCRQPBSHAPNH-UHFFFAOYSA-N
Physicochemical Property
logP
3.2596
Rotatable Bonds
6
Heavy Atom Count
28
Polar Areas
65.04
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44380906
ChEMBL ID
CHEMBL352905
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS