General Information of the Compound
Compound ID
CP0898126
Compound Name
1-(4-Chloro-phenyl)-cyclopentanecarboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide oxalic acid
    Show/Hide
Structure
Formula
C29H38ClN3O6
Molecular Weight
560.091
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)C2(c3ccc(Cl)cc3)CCCC2)CC1.O=C(O)C(=O)O
    Show/Hide
InChI
InChI=1S/C27H36ClN3O2.C2H2O4/c1-33-25-9-3-2-8-24(25)31-20-18-30(19-21-31)17-7-6-16-29-26(32)27(14-4-5-15-27)22-10-12-23(28)13-11-22;3-1(4)2(5)6/h2-3,8-13H,4-7,14-21H2,1H3,(H,29,32);(H,3,4)(H,5,6)
    Show/Hide
InChIKey
VLNQYVLKJNYJKD-UHFFFAOYSA-N
Physicochemical Property
logP
4.0346
Rotatable Bonds
9
Heavy Atom Count
39
Polar Areas
119.41
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
6
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44350920
ChEMBL ID
CHEMBL127080
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 56 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 42 nM
   TI
   LI
   LO
   TS