Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_85760-74-3
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 PubChem ID
CID: 54562
SID: 14822656
Canonical SMILES
CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12
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Compound Formula C13H21N3
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  9
1
EC50 = 3.1 nM
   TI
   LI
   LO
   TS
2
EC50 = 3.4 nM
   TI
   LI
   LO
   TS
3
EC50 = 5.2 nM
   TI
   LI
   LO
   TS
4
Ki = 0.41 nM
   TI
   LI
   LO
   TS
5
Ki = 15 nM
   TI
   LI
   LO
   TS
6
Ki = 23.99 nM
   TI
   LI
   LO
   TS
7
Ki = 24 nM
   TI
   LI
   LO
   TS
8
Ki = 100 nM
   TI
   LI
   LO
   TS
9
Ki = 420 nM
   TI
   LI
   LO
   TS
CL000389 CHO-DXB11
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 1.4 nM
   TI
   LI
   LO
   TS
2
EC50 = 2.1 nM
   TI
   LI
   LO
   TS
3
EC50 = 2.6 nM
   TI
   LI
   LO
   TS
4
EC50 = 2.9 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 2.6 nM
   TI
   LI
   LO
   TS
CL000153 CHOP
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 3.3 nM
   TI
   LI
   LO
   TS
2
EC50 = 8.4 nM
   TI
   LI
   LO
   TS
3
Ki = 43 nM
   TI
   LI
   LO
   TS
CL000025 HEK-293T
 Cell Line Info 
Homo sapiens (Human)  3
1
EC50 = 0.42 nM
   TI
   LI
   LO
   TS
2
EC50 = 1.778 nM
   TI
   LI
   LO
   TS
3
EC50 = 2.399 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  6
1
EC50 = 0.097 nM
   TI
   LI
   LO
   TS
2
EC50 = 2.4 nM
   TI
   LI
   LO
   TS
3
EC50 = 10 nM
   TI
   LI
   LO
   TS
4
Ki = 6.76 nM
   TI
   LI
   LO
   TS
5
Ki = 8.01 nM
   TI
   LI
   LO
   TS
6
Ki = 29.3 nM
   TI
   LI
   LO
   TS
CL000883 HTLA
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 2.6 nM
2 Ki = 12.5 nM