Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine
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 PubChem ID
CID: 10336538
SID: 15347559
Canonical SMILES
Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
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Compound Formula C18H19ClN4
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 5248.07 nM
   TI
   LI
   LO
   TS
2
Ki = 5300 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  8
1
Ki = 46 nM
   TI
   LI
   LO
   TS
2
Ki = 76 nM
   TI
   LI
   LO
   TS
3
Ki = 730 nM
   TI
   LI
   LO
   TS
4
Ki = 1600 nM
   TI
   LI
   LO
   TS
5
Ki = 2500 nM
   TI
   LI
   LO
   TS
6
Ki = 8300 nM
   TI
   LI
   LO
   TS
7
Ki = 9200 nM
   TI
   LI
   LO
   TS
8
Ki = 12000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5000 nM
2 Ki = 5300 nM