General Information of the Compound
Compound ID
CP0384047
Compound Name
4-methoxy-N,N-dimethyl-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonamide
    Show/Hide
Structure
Formula
C26H33N3O3S
Molecular Weight
467.635
Canonical SMILES
COc1ccc(cc1-c1ccc(CN2CCCCCC2c2ccccc2)[nH]1)S(=O)(=O)N(C)C
    Show/Hide
InChI
InChI=1S/C26H33N3O3S/c1-28(2)33(30,31)22-14-16-26(32-3)23(18-22)24-15-13-21(27-24)19-29-17-9-5-8-12-25(29)20-10-6-4-7-11-20/h4,6-7,10-11,13-16,18,25,27H,5,8-9,12,17,19H2,1-3H3
    Show/Hide
InChIKey
RQXJVDYSRNWVNF-UHFFFAOYSA-N
Physicochemical Property
logP
5.0579
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
65.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44212307
ChEMBL ID
CHEMBL280490
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.995 nM
   TI
   LI
   LO
   TS