General Information of the Compound
Compound ID
CP0656167
Compound Name
4'-chloro-2-methyl-biphenyl-4-sulfonic acid (3-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-yl)-amide
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Structure
Formula
C24H25ClN2O2S
Molecular Weight
440.996
Canonical SMILES
Cc1cc(S(=O)(=O)Nc2ccc3c(c2)CCN(C)CC3)ccc1-c1ccc(Cl)cc1
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InChI
InChI=1S/C24H25ClN2O2S/c1-17-15-23(9-10-24(17)19-3-6-21(25)7-4-19)30(28,29)26-22-8-5-18-11-13-27(2)14-12-20(18)16-22/h3-10,15-16,26H,11-14H2,1-2H3
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InChIKey
UAJYHPWCBGWDNL-UHFFFAOYSA-N
Physicochemical Property
logP
5.14662
Rotatable Bonds
4
Heavy Atom Count
30
Polar Areas
49.41
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10216820
SID: 15215859
ChEMBL ID
CHEMBL230069
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 31.62 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 6.31 nM
   TI
   LI
   LO
   TS