General Information of the Compound
Compound ID
CP0458824
Compound Name
N-[4-[2-[(6R)-6-(dipropylamino)-1-methoxy-5,6,7,8-tetrahydronaphthalen-2-yl]ethyl]phenyl]methanesulfonamide
    Show/Hide
Structure
Formula
C26H38N2O3S
Molecular Weight
458.668
Canonical SMILES
CCCN(CCC)[C@@H]1CCc2c(C1)ccc(CCc1ccc(NS(C)(=O)=O)cc1)c2OC
    Show/Hide
InChI
InChI=1S/C26H38N2O3S/c1-5-17-28(18-6-2)24-15-16-25-22(19-24)12-11-21(26(25)31-3)10-7-20-8-13-23(14-9-20)27-32(4,29)30/h8-9,11-14,24,27H,5-7,10,15-19H2,1-4H3/t24-/m1/s1
    Show/Hide
InChIKey
ZINAGLZHGNCAAM-XMMPIXPASA-N
Physicochemical Property
logP
4.8312
Rotatable Bonds
11
Heavy Atom Count
32
Polar Areas
58.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
32

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44353346
ChEMBL ID
CHEMBL130680
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS